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Article: DimaXx
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Description:
Liquid Creatine Research
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The many benefits the user can expect from taking a creatine
supplement have long been known: improved performance in sport, greater vitality
and capacity for work in everyday life, and speedier recovery from illness.
After the sprinter Linford Christie won an Olympic gold medal in 1992, the use
of creatine supplements really became the subject of much discussion and
research.
1. Biochemical bases
Creatine - or, to give it its chemical name, a-Methylguanidoacetic acid - is a
naturally occurring endogenic substance which plays a major part in the
metabolic process of the entire body and is just as vital for human existence as
proteins, vitamins and minerals. The substance was discovered as long ago as
1832 as a component part of beef tea. Justus von Liebig demonstrated the
presence of the energy carrier in 1847 in the tissue of various mammals.
The name 'creatine' is derived from the Greek word for meat(kreas). The
substance is produced in the liver and also in the kidneys from the amino acids
glycin, arginine and methionine, or it enters the organism via food, in
particular through eating meat and fish.
The body of an adult weighing 70 kg can store between 100 and 120 grams of this
form of energy in the heart, the brain and the skeletal muscles. With a mixed
diet containing no creatine supplement, an average of one gram of creatine per
day is ingested. On average, the body converts two grams of creatine a day,
which it loses through elimination of the catabolic product creatinine. In the
muscles, with the aid of the enzyme creatinekinase, creatine forms the
energy-rich compound creatine phosphate by means of transphosphorylation. In
this reaction catalyzed by creatinekinase, ATP is converted into ADP.
This chemical source of energy supplies the entire body. The skeleton, the
muscles, the cell environment and the internal organs all require a continuous
supply of creatine phosphate for ensure anabolism, maintenance of the body and
proper functioning. Research has shown that the substance has outstanding
properties as an energy buffer and in particular as an energy catalyst.
2. Function and effect of creatine phosphate
The human body transforms food by means of a large number of chemical processes
into various substances, including adenosintriphosphate (ATP). If a large amount
of creatine phosphate is stored in the muscle, it is able to perform well. The
reason for this is that ATP is the universal fuel for muscles needed by all
living organisms as a source of energy.
The ingestion of creatine provides muscles with an additional source of energy,
and this produces a range of different effects. In articles written by Melchior
(1996) and Brönnimann (1998) both appearing in the sports magazine "Leistungssport",
creatine is alleged to have a very wide range of effects, implying primarily and
from a sports point of view speed, stamina and strength. Paul Greenhaff, of the
Nutritional Committee of the British Olympic Association, also praises the
positive effects of creatine for all endogenic biological processes requiring
high energy consumption levels.
The results of latest research conclude that, in addition to athletes and peak
performers in the world of sport, people who are required to perform under
pressure in their work and in everyday life can increase their wellbeing by
taking creatine. Studies into the muscle mass and strength-building properties
of creatine point in the same direction, too: greater vitality and shorter
convalescence times. It is precisely in the recovery stage that a boost can be
given to the revitalization of muscle power. Creatine is also used to strengthen
the body's immune system. Many people outside the field of high-performance
sport who take creatine report its positive effects on the performance of the
brain and memory and refer to a greater resistance to stress since they began
supplementing their diet with creatine. Many of those taking part in trials with
creatine are able to recover more rapidly and need less sleep.
Moreover, there is evidence of the successful application of creatine for
increasing the stability of bone and cartilage mass. Series of tests show that
bones and cartilage respond positively to the ingestion of creatine. With regard
to bone fractures, to the regression of bone tissue and associated late symptoms
(osteoporosis), creatine is an important stabilizer which can aid the healing
process and retard the process of bone mass loss.
3. Dosage, duration and presentation of creatine
supplement
There are various prescriptions available as far as the presentation of creatine
is concerned. The customer has a choice of powder, capsules and special liquid
serum. However, everyone is of the opinion that creatine should be taken as part
of a course of treatment. A course consists of a one-week 'priming phase' and a
four to six-week 'continuation phase', followed by a 'rest phase' of at least
two months so that the endogenic production of creatine is not inhibited.
Experiments on animals have shown that chronic feeding of very high doses of
creatine can reduce the autonomic synthesis of creatine in the body.
Powder form seems to have become most popular in practice. Nevertheless, there
is still no shortage of continued specific customer requests for a more
appropriate form which allows creatine to enter the bloodstream more quickly.
Taking into account customers' changing requirements, great care was placed on
the development of a liquid serum leading to significant increases in
performance when taken in smaller, more efficient amounts. A further advantage
is that ingestion of a smaller quantity places less strain on the digestion
process, leaving more energy for the building of muscle in the body.
The creatine monohydrate (CrH2O) dosage normally taken as a supplement is 20
grams per day. This is taken in four portions of 5 grams each by mouth, as
muscle is unable to absorb large amounts of creatine at any one time. The dosage
is repeated over five to six days (the 'priming phase'). This application
pattern is based on the research results of Harris (1992) and Hultman.
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Description:
DimaXx
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Caution: For any suspected or known illness or
dysfunction, always consult your physician for medical diagnosis and treatment
first. Statements contained herein have not been evaluated by the Food and Drug
Administration. Products mentioned herein are not intended to diagnose, treat,
cure, or prevent any disease.
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